YES! After learning to play guitar this became super obvious to me. Musicians tweak a dozen analog knobs in pursuit of ‘good tone’ and often have no means to store their settings. Nor do they care. They are in creation mode, in the mood, in the moment. It’ll be different next time, let alone in a live performance. I have limits to my audiophile equipment pursuits because I know that subtle nuances were often randomly created and incidental to a musician’s emotive communication.